Source:http://www.reactome.org/biopax/48887BiochemicalReaction2359
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Authored: Garapati, P V, 2010-10-29,
Edited: Garapati, P V, 2010-10-29,
Interaction of E3 with both substrate and E2-Ub, brings them into proximity so that ubiquitin is transferred from E2 to the substrate. In most cases the transfer of ubiquitin is direct from E2 to substrate, but in a small subset of E3s, it occurs via a covalent E3-Ub thioester intermediate (Raymond et al. 2009).,
Reviewed: Elliott, T, 2011-02-10
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Transfer of Ub from E2 to substrate and release of E2
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6.3.2.19
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