Source:http://www.reactome.org/biopax/48887BiochemicalReaction2327
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Authored: Garapati, P V, 2008-12-16 11:12:19,
Edited: Garapati, P V, 2008-12-16 11:12:19,
Once phosphorylated, SH2-domain containing tyrosine phosphatases SHP-1 and SHP-2 bind to the ITIM and ITSM motifs of PD-1. The association between SHP-1 and PD-1 appears to be weaker than the interaction of PD-1 with SHP-2.,
Reviewed: Bluestone, JA, Esensten, J, 2009-06-01 18:47:33
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Interaction of SHP-1 or SHP-2 with phospho PD-1
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