Source:http://www.reactome.org/biopax/48887BiochemicalReaction2316
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Authored: Garapati, P V, 2008-12-16 11:12:19,
Edited: Garapati, P V, 2008-12-16 11:12:19,
Reviewed: Bluestone, JA, Esensten, J, 2009-06-01 18:47:33,
Vav1 serves as a GEF for Cdc42-GTPase. It interacts with and activates Cdc42. The activated Cdc42 in turn transmits its signals through the downstream target, the PAK1 kinase.
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Activation of Cdc42 by pVav1
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