Source:http://www.reactome.org/biopax/48887BiochemicalReaction2293
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After the phosphorylation and activation CARMA1 undergoes oligomerization, likely through its CC domain. CARMA1 is thought to oligomerize first as a trimer which triggers downstream oligomerization cascade that is ultimately necessary for the subsequent activation of the IKK complex.,
Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10,
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
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Oligomerization of CARMA1
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