Source:http://www.reactome.org/biopax/48887BiochemicalReaction2284
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Authored: Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10,
PI3K enzyme bound to adaptor protein TRIM, uses phosphatidylinositol 4,5-bisphosphate (PIP2) as its substrate and phosphorylates it to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). This PIP3 acts as a membrane anchor for the downstream proteins like PDK1 and PKB.,
Reviewed: Trowsdale, J, 2008-02-26 12:02:59
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PI3K phosphorylates PIP2 to PIP3
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2.7.1.153
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