Source:http://www.reactome.org/biopax/48887BiochemicalReaction1964
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Authored: Dall'Olio, GM, 2009-11-10,
Edited: Jassal, B, 2009-11-10,
In the last step of the N-glycan precursor biosynthesis pathway, the mature N-glycan (Glc3Man9GlcNAc2) is removed from the dolichyl diphosphate molecule upon which it has been synthesized, and attached to a nascent protein. In this process, a dolichyl diphosphate molecule is released and once de-phosphorylated by dolichyl diphosphatase 1 (DOLPP1) to obtain dolichyl phosphate, it can be used as a substrate for the synthesis of another N-glycan oligosaccharide (Wedgwood JF and Strominger JL, 1980).,
Reviewed: Gagneux, P, 2010-04-16
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Dephosphorylation of dolichyl diphosphate
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3.6.1.43
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