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Authored: Johansson, HE, 2007-11-28 23:26:30, Edited: D'Eustachio, P, 2007-11-28 23:33:46, Reviewed: Jassal, B, 2008-01-28 15:51:00, The reaction of EIF5A, spermidine, and NAD+ to form EIF5A(Dhp), 1,3-diaminopropane, and NADH + H+ is reversible in vitro. Under physiological conditions, the reverse reaction is probably minimized by the rapid, irreversible conversion of FIF5A(Dhp) to EIF5A(Hyp).
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EIF5A(Dhp) + 1,3-diaminopropane <=> EIF5A + spermidine
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2.5.1.46
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