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biopax3:comment |
Authored: May, B, 2009-07-22,
Edited: May, B, 2009-07-22,
Reviewed: Wilusz, J, 2009-09-17,
The DCP1-DCP2 decapping complex binds the 7-methylguanosine cap of mRNA and hydrolyzes the triphosphate bond to yield 7-methylguanosine 5'-diphosphate and RNA with 5'-monophosphate. The DCP2 subunit of the complex catalyzes the hydrolysis. DCP2 has higher affinity for some subsets of mRNA.
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