Source:http://www.reactome.org/biopax/48887BiochemicalReaction1863
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Activation of the PI3K pathway has been demonstrated downstream of a number of FGFR mutants (reviewed in Wesche, 2001; see for instance, Agazie, 2003; Kunii, 2008; Takeda, 2007; Chen, 2004; Demiroglu, 2001; Guasch, 2001; Byron, 2008), and is presumed to occur in a manner analogous to the wild-type receptor.,
Authored: Rothfels, K, 2012-02-09,
Edited: Rothfels, K, 2012-05-16,
Reviewed: Ezzat, S, 2012-05-15
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| biopax3:xref |
http://identifiers.org/pubmed/11689702,
http://identifiers.org/pubmed/11739186,
http://identifiers.org/pubmed/14534538,
http://identifiers.org/pubmed/15448205,
http://identifiers.org/pubmed/17505008,
http://identifiers.org/pubmed/18757403,
http://identifiers.org/pubmed/21711248,
urn:biopax:UnificationXref:REACTOME DATABASE ID_1986645,
urn:biopax:UnificationXref:REACTOME_REACT_120860_1
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| biopax3:displayName |
Recruitment of the catalytic subunit of PI3K by activated FGFR1 mutants
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