Source:http://www.reactome.org/biopax/48887BiochemicalReaction1858
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| rdf:type | |
| biopax3:comment |
After activation, FGFR mutants are presumed to recruit FRS2alpha. This has been demonstrated in some cases (see for instance Ahmed, 2008; Weiss, 2010; Dutt, 2008; Dutt, 2011; Cha, 2009; Qing, 2009; Bai, 2010 ) and is inferred to occur in others by analogy with the wild-type receptor.,
Authored: Rothfels, K, 2012-02-09,
Edited: Rothfels, K, 2012-05-16,
Reviewed: Ezzat, S, 2012-05-15
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| biopax3:xref |
http://identifiers.org/pubmed/18373495,
http://identifiers.org/pubmed/18552176,
http://identifiers.org/pubmed/19103595,
http://identifiers.org/pubmed/19381019,
http://identifiers.org/pubmed/20709759,
http://identifiers.org/pubmed/21160078,
http://identifiers.org/pubmed/21666749,
urn:biopax:UnificationXref:REACTOME DATABASE ID_1982073,
urn:biopax:UnificationXref:REACTOME_REACT_120949_1
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| biopax3:dataSource | |
| biopax3:displayName |
Activated FGFR mutants bind FRS2alpha
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| biopax3:left | |
| biopax3:right |