Source:http://www.reactome.org/biopax/48887BiochemicalReaction1788
| Predicate | Object |
|---|---|
| rdf:type | |
| biopax3:comment |
Authored: Rothfels, K, 2011-08-15,
Once recruited to the activated receptor, PI3K phosphorylates PIP2 to PIP3, leading to activation of AKT signaling. PI3K signaling has been demonstrated in ZMYM2-, FOP- and BCR-FGFR1 fusions (Chen, 2004; Demiroglu, 2001; Guasch, 2001), as well as downstream of a number of other FGFR mutants (see for instance, Byron, 2008; Kunii, 2008; Agazie, 2003; Takeda, 2007).,
Reviewed: Gotoh, N, 2011-08-26
|
| biopax3:xref | |
| biopax3:dataSource | |
| biopax3:displayName |
FGFR associated PI3K phosphorylates PIP2 to PIP3
|
| biopax3:left | |
| biopax3:right |