Source:http://www.reactome.org/biopax/48887BiochemicalReaction1786
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Authored: Rothfels, K, 2011-08-15,
Reviewed: Gotoh, N, 2011-08-26,
The 110 kDa catalytic subunit (PIK3CA) binds to the 85 kDa regulatory subunit (PIK3R1) to create the active PIK3.
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PI3K catalytic subunit binds to GRB2:GAB1:PI3Kreg (indirect)
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