Source:http://www.reactome.org/biopax/48887BiochemicalReaction1783
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Authored: Rothfels, K, 2011-08-15,
Reviewed: Gotoh, N, 2011-08-26,
The direct GRB2-binding sites of FRS2alpha have a major role in activation of the PI3K pathway.
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GRB2:GAB1:PI3Kreg binds directly to p-FRS2:activated FGFR
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