Source:http://www.reactome.org/biopax/48887BiochemicalReaction1775
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Authored: Rothfels, K, 2011-08-15,
Reviewed: Gotoh, N, 2011-08-26,
SOS, recruited by GRB2:p-FRS2 to activated FGFR, activates RAS nucleotide exchange from the inactive GDP-bound to the active GTP-bound state.
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Ras nucleotide exchange by GRB2:SOS1 bound to p-FRS2:activated FGFR
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