Source:http://www.reactome.org/biopax/48887BiochemicalReaction1771
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Authored: de Bono, B, 2007-01-10 10:27:18,
Edited: Jupe, S, 2010-02-03,
FRS2beta is activated through tyrosine phosphorylation catalyzed by the protein kinase domain of the activated FGFR. By sequence comparison, FRS2beta has the 2 SHP2-binding sites and has three of the four GRB2-binding sites.,
Reviewed: Gotoh, N, 2011-08-26,
Reviewed: Mohammadi, M, 2007-02-06 21:44:35
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Phosphorylation of FRS2-beta by activated FGFR
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2.7.10
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