Source:http://www.reactome.org/biopax/48887BiochemicalReaction1749
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Authored: May, B, 2009-06-10,
Edited: May, B, 2009-06-10,
Reviewed: Zhang, Weizhen, 2009-08-29,
The majority of circulating ghrelin is not acylated (des-acyl ghrelin). Acyl ghrelin can be deacylated in the bloodstream by butyrylcholinesterase and platelet-activating factor acetylhydrolase, which are associated with circulating lipids. Other enzymes may also have this capability. It is unknown if a portion of des-acyl ghrelin in the bloodstream is generated by direct synthesis and secretion.
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Deacylation of Acyl Ghrelin
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3.1
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