Source:http://www.reactome.org/biopax/48887BiochemicalReaction1745
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Authored: May, B, 2009-06-10,
Edited: May, B, 2009-06-10,
Proghrelin is octanoylated by ghrelin O-acyltransferase (GOAT/MBOAT4), an enzyme present in the endoplasmic reticulum membrane which both transports the octanoic acid substrate and condenses it on the hydroxyl group of serine-3 of the mature protein. The most common acylated form of ghrelin is octanoyl ghrelin but decanoyl ghrelin is also detected. Ghrelin is the only protein known to undergo such a modification.,
Reviewed: Zhang, Weizhen, 2009-08-29
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http://identifiers.org/pubmed/12414809,
http://identifiers.org/pubmed/18396350,
http://identifiers.org/pubmed/18443287,
http://identifiers.org/pubmed/19280057,
http://identifiers.org/pubmed/19628676,
urn:biopax:UnificationXref:REACTOME DATABASE ID_422104,
urn:biopax:UnificationXref:REACTOME_REACT_19318_2
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Octanoylation of Proghrelin by Ghrelin O-acyltransferase
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