Source:http://www.reactome.org/biopax/48887BiochemicalReaction1728
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Edited: May, B, Gopinathrao, G, 2008-11-19 20:02:07,
IGFBP 1 binds IGF I or IGF II via the conserved N terminus and C terminus of IGFBP 1. IGFBP 1 is enriched in amniotic fluid and is produced in the liver under control of insulin (insulin suppresses production). IGFBP 1 acts to stimulate IGF function. It is unknown which if any protease degrades IGFBP 1.,
Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31
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| biopax3:xref |
http://identifiers.org/pubmed/12379487,
http://identifiers.org/pubmed/12466191,
http://identifiers.org/pubmed/17047378,
http://identifiers.org/pubmed/7519608,
http://identifiers.org/pubmed/7543116,
http://identifiers.org/pubmed/7683646,
http://identifiers.org/pubmed/7689487,
http://identifiers.org/pubmed/8781553,
http://identifiers.org/pubmed/9733769,
urn:biopax:UnificationXref:REACTOME DATABASE ID_381487,
urn:biopax:UnificationXref:REACTOME_REACT_15321_2
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Formation of the IGF:IGFBP-1 Complex
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