Source:http://www.reactome.org/biopax/48887BiochemicalReaction1722
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Authored: May, B, 2009-06-02 00:51:49,
Edited: May, B, 2009-06-02 00:51:49,
Phosphorylation of the C-terminal region causes a loop in the C-terminus to change position, enabling access to an ADP-binding pocket. Phosphorylated IRE1-alpha dimers bind ADP in preference to ATP.,
Reviewed: D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31,
Reviewed: Urano, F, 2010-04-30
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ADP Binding by Phosphorylated IRE1 Homodimer
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