Source:http://www.reactome.org/biopax/48887BiochemicalReaction1631
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Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07,
Reviewed: Greene, LA, 2007-11-08 15:39:37,
The PI3K network is negatively regulated by phospholipid phosphatases that dephosphorylate PIP3, thus hampering AKT activation. The tumour supressor PTEN is the primary phospholipid phosphatase.
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PTEN dephosphorylates PIP3
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3.1.3.67
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