Source:http://www.reactome.org/biopax/48887BiochemicalReaction1332
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Authored: May, B, 2011-01-27,
Edited: May, B, 2011-01-27,
NODAL receptors signal by phosphorylating SMAD2 and SMAD3 (Bondestam et al. 2001, Kumar et al. 2001, DaCosta Byfield et al. 2004). As in TGF-beta signaling, Smad anchor for receptor activation (SARA) may bind and present SMAD2 and SMAD3 for phosphorylation but this has not yet been demonstrated in NODAL signaling.,
Reviewed: Peng, C, 2011-08-24
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Phosphorylation of R-SMAD2/3 by NODAL Receptor
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2.7.11
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