Source:http://www.reactome.org/biopax/48887BiochemicalReaction1331
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As inferred from the response of the activin receptor to activin, the type II component of the NODAL receptor phosphorylates the type I component in response to NODAL binding. As inferred from mouse and frog (Xenopus) NODAL can signal via the ACVR1C (ALK7) type I activin receptor (Reissman et al. 2001) though this may be dispensable for development in mouse (Jornvall et al. 2004).,
Authored: May, B, 2011-01-23,
Edited: May, B, 2011-01-23,
Reviewed: Peng, C, 2011-08-24
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Type II Activin Receptor (ActRIIB/ACVR2B) Phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in Response to NODAL
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2.7.11
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