Source:http://www.reactome.org/biopax/48887BiochemicalReaction1330
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As inferred from the response of the activin receptor to activin, the type II component of the NODAL receptor phosphorylates the type I component in response to NODAL binding. Experiments with human proteins in frog oocytes show NODAL can signal via the CRIPTO:ACVR1B(ALK4):ACVR2 complex (Yeo and Whitman 2001).,
Authored: May, B, 2011-01-23,
Edited: May, B, 2011-01-23,
Reviewed: Peng, C, 2011-08-24
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Type II Activin Receptor (ActRII/ACVR2) Phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in Response to NODAL
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2.7.11
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