Source:http://www.reactome.org/biopax/48887BiochemicalReaction1293
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Authored: Garapati, P V, 2008-07-30 10:22:58,
Edited: Garapati, P V, 2008-07-30 10:22:58,
L1 and RanBPM interact with one another and the N-terminus of RanBPM was sufficient for the interaction with L1. RanBPM interacts with RAN, a Ras-like small GTPase that functions as a carrier in nuclear-cytoplasmic exchange. It directly interacts with Sos to activate Ras and induce ERK phosphorylation. RanBPM might function as an adaptor to mediate L1-induced ERK activation.,
Reviewed: Maness, PF, 2010-02-16
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L1 binds RanBPM
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