Source:http://www.reactome.org/biopax/48887BiochemicalReaction1288
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Authored: Garapati, P V, 2008-07-30 10:22:58,
Edited: Garapati, P V, 2008-07-30 10:22:58,
L1CAM binds with high affinity to the proteoglycan neurocan. Neurocan binds to the first Ig domain of L1CAM through its sushi module and a chondroitin sulphate chain. This interaction interferes with the homophilic interaction of L1CAM and inhibits neuronal adhesion and neurite extension mediated by L1CAM.,
Reviewed: Maness, PF, 2010-02-16
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Interaction of L1 with Neurocan
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