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A key event for Ras transformation involves the direct physical association between Ras and the Raf-1 kinase. This interaction promotes both Raf translocation to the plasma membrane and activation of Raf kinase activity., Authored: Williams, MG, 2007-10-30 11:44:05, Edited: Jupe, S, 2010-08-06, Reviewed: Dooms, H, 2011-03-17, Reviewed: Villarino, A, 2011-02-11
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Phosphorylated human RAF1 binds to RAS:GTP complex
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