Source:http://www.reactome.org/biopax/48887BiochemicalReaction1155
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Authored: Garapati, P V, 2009-03-23 09:59:28,
Edited: Garapati, P V, 2009-03-23 10:00:07,
LIM-kinase is responsible for the tight regulation of the activity of cofilin (a protein that depolymerizes actin filaments) and thus maintains the balance between actin assembly and disassembly. LIMK is one of the downstream targets of PAK1 and is activated through phosphorylation by PAK1 on T508 within its activation loop.,
Reviewed: Kumanogoh, A, Kikutani, H, 2009-09-01
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Phosphorylation of LIMK-1 by PAK
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2.7.11
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