Source:http://www.reactome.org/biopax/48887BiochemicalReaction1043
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Authored: Ouwehand, W.H., 2007-11-12 16:45:54,
JAM-A is the most widely expressed member of the family, and has been shown to be expressed on endothelial and epithelial cells, on platelets, and on a number of leukocyte subsets. In endothelial cells, JAM-A locates to the tight junctions, where it appears to engage in homophilic binding to JAM-A on adjacent cells, an interaction that is considered to play a critical role in angiogenesis.,
Reviewed: Zwaginga, JJ, 2007-11-12 16:47:00
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JAM-A homodimerises
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