Source:http://www.reactome.org/biopax/48887BiochemicalReaction1003
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Activated kallikrein binds to alpha2-macroglobulin (Sottrup-Jensen et al. 1984), forming a stable and enzymatically inactive complex. Under normal conditions in vivo, this reaction appears to be responsible for the inactivation of about 1/6 of activated kallikrein (with C1Inh responsible for the inactivation of about 5/6) (Harpel et al. 1985).,
Authored: D'Eustachio, P, 2005-01-20 14:44:36
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kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin
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