Protein that inhibits both nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. The nAChR is a postsynaptic membrane protein that, after binding acetylcholine, responds by an extensive change in conformation, which leads to opening of an ion-conducting channel across the plasma membrane. The mAChR is a membrane protein that acts through G proteins and mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
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Protein that inhibits both nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. The nAChR is a postsynaptic membrane protein that, after binding acetylcholine, responds by an extensive change in conformation, which leads to opening of an ion-conducting channel across the plasma membrane. The mAChR is a membrane protein that acts through G proteins and mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.
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AChR inhibitor,
Acetylcholine receptor inhibitor
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