The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
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|---|---|
| rdf:type | |
| rdfs:comment |
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
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| rdfs:subClassOf | |
| rdfs:label |
3'-5' NMD,
3'-5' nonsense-mediated decay,
3'-5' nonsense-mediated mRNA decay,
nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay,
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay,
nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay,
nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
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| skos:exactMatch |