Linked Life Data

histone demethylase activity (H3-K36 specific)

Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein.

Source:http://purl.uniprot.org/go/0051864

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PredicateObject
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Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein.
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H3-K36-specific demethylase activity, JHDM1A activity, JmjC domain-containing histone demethylase 1A activity, [histone-H3]-lysine-36 demethylase activity, histone H3-lysine-36 demethylase activity, histone demethylase activity (H3-K36 specific), histone-lysine (H3-K36) demethylase activity, histone-lysine demethylase activity (H3-K36 specific), histone-lysine(H3-K36) demethylase activity, protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity, protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity
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