The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
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| rdf:type | |
| rdfs:comment |
The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
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| rdfs:subClassOf | |
| rdfs:label |
class switch recombination,
class switching,
isotype switch recombination,
isotype switching
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| skos:exactMatch | |
| skos:narrower |