Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH.
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Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH.
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(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating),
3-hydroxy-3-methylglutaryl coenzyme A reductase activity,
3-hydroxy-3-methylglutaryl-coenzyme A reductase activity,
HMG-CoA reductase activity,
beta-hydroxy-beta-methylglutaryl CoA-reductase activity,
beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity,
hydroxymethylglutaryl coenzyme A reductase activity,
hydroxymethylglutaryl-CoA reductase (NADH) activity,
hydroxymethylglutaryl-CoA reductase activity
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