Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by interacting selectively and non-covalently with MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.
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| rdf:type | |
| rdfs:comment |
Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by interacting selectively and non-covalently with MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.
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| rdfs:subClassOf | |
| rdfs:label |
suppression by virus of host MDA-5 activity via MDA-5 binding,
suppression by virus of host MDA5 activity by MDA-5 binding
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| skos:exactMatch |