A series of molecular signals initiated by an extracellular signal combining with a dimeric receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Heterodimeric and homodimeric GPCRs may have different functional properties from those of the respective monomers.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
A series of molecular signals initiated by an extracellular signal combining with a dimeric receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Heterodimeric and homodimeric GPCRs may have different functional properties from those of the respective monomers.
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| rdfs:subClassOf | |
| rdfs:label |
G-protein coupled receptor signaling pathway via GPCR dimer,
dimeric G-protein coupled receptor signaling pathway,
dimeric G-protein coupled receptor signalling pathway
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| skos:exactMatch |