Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
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Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
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S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity,
S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity,
histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity,
histone-lysine N-methylase activity,
histone-lysine N-methyltransferase activity,
protein (lysine) methyltransferase activity,
protein methylase 3 activity,
protein methylase III activity,
protein methyltransferase II activity
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