An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
|
| rdfs:subClassOf | |
| rdfs:label |
JNK cascade,
JNK1 cascade,
JNK2 cascade,
JNK3 cascade,
MAPK10 cascade,
MAPK8 cascade,
MAPK9 cascade,
SAPK cascade,
c-Jun N-terminal kinase cascade,
stress-activated protein kinase cascade
|
| skos:exactMatch | |
| skos:narrower |