The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
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| rdfs:subClassOf | |
| rdfs:label |
GPI anchor anabolism,
GPI anchor biosynthesis,
GPI anchor biosynthetic process,
GPI anchor formation,
GPI anchor synthesis,
GPI/GSI anchor biosynthesis,
GPI/GSI anchor biosynthetic process,
glycosylphosphatidylinositol biosynthesis,
glycosylphosphatidylinositol biosynthetic process
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| skos:exactMatch | |
| skos:narrower |
http://purl.uniprot.org/go/0016254,
http://purl.uniprot.org/go/0016255,
http://purl.uniprot.org/go/0018265,
http://purl.uniprot.org/go/0018266,
http://purl.uniprot.org/go/0018267,
http://purl.uniprot.org/go/0018268,
http://purl.uniprot.org/go/0018269,
http://purl.uniprot.org/go/0018270,
http://purl.uniprot.org/go/0050493
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| uniprot:replaces |