Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
| Predicate | Object |
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| rdf:type | |
| rdfs:comment |
Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
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| rdfs:subClassOf | |
| rdfs:label |
ATP:protein phosphotransferase (MAPKK-activated) activity,
Dp38,
ERK,
ERK1,
ERK2,
LeMPK3,
MAP kinase 1 activity,
MAP kinase 2 activity,
MAP kinase activity,
MAP-2 kinase activity,
MAPK,
MBP kinase I activity,
MBP kinase II activity,
MP kinase activity,
Mpk2,
PMK-1,
PMK-2,
PMK-3,
SAPK2,
STK26,
extracellular signal-regulated kinase activity,
mitogen activated kinase activity,
mitogen-activated protein kinase activity,
myelin basic protein kinase activity,
p38,
p38-2,
p38delta,
p42 mitogen-activated protein kinase activity,
p42mapk,
p44mpk,
pp42,
pp44mapk
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| uniprot:replaces |