DNA topoisomerase II

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

Source:http://purl.uniprot.org/go/0003918

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Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
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DNA gyrase activity, DNA topoisomerase (ATP-hydrolysing), DNA topoisomerase (ATP-hydrolyzing) activity, DNA topoisomerase II, DNA topoisomerase IV activity, DNA topoisomerase type II activity, DNA-gyrase activity, deoxyribonucleate topoisomerase, deoxyribonucleic topoisomerase activity, topoisomerase, topoisomerase II, type II DNA topoisomerase activity
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