The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
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| rdf:type | |
| rdfs:comment |
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
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| rdfs:subClassOf | |
| rdfs:label |
HDR,
HRR,
Rad51-dependent recombinational repair,
Rhp51-dependent recombinational repair,
double-strand break repair via homologous recombination,
homologous recombinational repair,
homology-directed repair
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| skos:exactMatch | |
| skos:narrower | |
| uniprot:replaces |