Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
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Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
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catalytic spliceosome assembly for second transesterification step,
formation of catalytic U12-type spliceosome for second transesterification step,
formation of catalytic U2-type spliceosome for second transesterification step,
formation of catalytic spliceosome for second transesterification step,
formation of spliceosomal A2-2 complex,
formation of spliceosomal C1 complex,
generation of catalytic spliceosome for second transesterification step,
lariat formation, 5'-splice site cleavage,
spliceosomal A2-3 complex biosynthesis,
spliceosomal A2-3 complex formation,
spliceosomal C2 complex biosynthesis,
spliceosomal C2 complex formation
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