Aerobactin is one of a group of high-affinity iron chelators known as siderophores and is produced under conditions of iron deprivation.
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Aerobactin is one of a group of high-affinity iron chelators known as siderophores and is produced under conditions of iron deprivation.,
It is a dihydroxamate comprising two molecules of N(6)-acetyl-N(6)-hydroxy-L-lysine and one molecule of citrate.,
This enzyme catalyzes the first of two synthase reactions to link N(6)-acetyl-N(6)-hydroxy-L-lysine and citrate.
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| uniprot:name |
N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase,
N(alpha)-citryl-N(epsilon)-acetyl-N(epsilon)-hydroxylysine synthase
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| uniprot:activity |
2 ATP + citrate + N(6)-acetyl-N(6)-hydroxy-L-lysine + H(2)O = 2 ADP + 2 phosphate + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine.
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| uniprot:cofactor |
Magnesium
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