D-alanine--D-serine ligase

The resulting peptidoglycan does not bind the glycopeptide antibiotics vancomycin and teicoplanin, conferring resistance on the bacteria.

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Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide, which is formed by EC 6.3.2.4, D-alanine--D-alanine ligase., The resulting peptidoglycan does not bind the glycopeptide antibiotics vancomycin and teicoplanin, conferring resistance on the bacteria.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/6.3.2.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/6.3.2.-
uniprot:name	D-alanine--D-serine ligase
uniprot:activity	D-alanine + D-serine + ATP = D-alanyl-D-serine + ADP + phosphate.