UDP-N-acetylmuramyl-tripeptide synthetase

Involved with EC 6.3.2.4, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.

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Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	uniprot:Enzyme
rdfs:comment	Involved with EC 6.3.2.4, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide., It is the amino group of the L-center of the diaminopimelate that is acylated., This enzyme adds diaminopimelate in Gram-negative organisms and in some Gram-positive organisms; in others EC 6.3.2.7 adds lysine instead.
rdfs:subClassOf	http://purl.uniprot.org/enzyme/6.3.2.-
skos:broaderTransitive	http://purl.uniprot.org/enzyme/6.3.2.-
uniprot:name	MurE synthetase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming), UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase, UDP-N-acetylmuramyl-tripeptide synthetase
uniprot:activity	ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diamino-heptanedioate.