3-hydroxybenzoate--CoA ligase

The enzyme works equally well with 4-hydroxybenzoate but shows low activity toward benzoate, 4-aminobenzoate, 3-aminobenzoate, 3-fluorobenzoate, 4-fluorobenzoate, 3-chlorobenzoate, and 4-chlorobenzoate.

Source:http://purl.uniprot.org/enzyme/6.2.1.37

Statements in which the resource exists as a subject.
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The enzyme works equally well with 4-hydroxybenzoate but shows low activity toward benzoate, 4-aminobenzoate, 3-aminobenzoate, 3-fluorobenzoate, 4-fluorobenzoate, 3-chlorobenzoate, and 4-chlorobenzoate., There is no activity with 3,4-dihydroxybenzoate, 2,3-dihydroxybenzoate, and 2-hydroxybenzoate as substrates.
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3-hydroxybenzoate--CoA ligase, 3-hydroxybenzoate--coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl-CoA synthetase
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ATP + 3-hydroxybenzoate + CoA = AMP + diphosphate + 3-hydroxybenzoyl-CoA.