The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.,
The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.,
The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
Cyclophilin,
PPIase,
Peptidyl-prolyl cis-trans isomerase,
Peptidylprolyl cis-trans isomerase,
Peptidylprolyl isomerase,
Rotamase
|
| uniprot:activity |
Peptidylproline (omega=180) = peptidylproline (omega=0).
|