The enzyme from the hyperthermophilic eubacterium Thermus thermophilus can catalyze the reaction shown above but cannot catalyze the previously described reaction, i.e. formation of homocitrate by hydration of cis-homoaconitate.
| Predicate | Object |
|---|---|
| rdf:type | |
| rdfs:comment |
The enzyme from the hyperthermophilic eubacterium Thermus thermophilus can catalyze the reaction shown above but cannot catalyze the previously described reaction, i.e. formation of homocitrate by hydration of cis-homoaconitate.,
The enzyme responsible for the conversion of cis-homoaconitate into homocitrate in T.thermophilus is unknown at present but the reaction can be catalyzed in vitro using EC 4.2.1.3 from pig.
|
| rdfs:subClassOf | |
| skos:broaderTransitive | |
| uniprot:name |
2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase,
Cis-homoaconitase,
HACN,
Homoaconitase,
Homoaconitate hydratase
|
| uniprot:activity |
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate = (Z)-but-1-ene-1,2,4-tricarboxylate + H(2)O.
|
| uniprot:cofactor |
Iron-sulfur
|