Phosphoribosylaminoimidazole carboxylase

While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in Escherichia coli, namely EC 6.3.4.18 and EC 5.4.99.18.

Source:http://purl.uniprot.org/enzyme/4.1.1.21

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
rdfs:comment
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate., While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in Escherichia coli, namely EC 6.3.4.18 and EC 5.4.99.18.
rdfs:subClassOf
skos:broaderTransitive
uniprot:name
1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase, 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase, 5-amino-1-ribosylimidazole 5-phosphate carboxylase, 5-phosphoribosyl-5-aminoimidazole carboxylase, AIR carboxylase, Phosphoribosylaminoimidazole carboxylase
uniprot:activity
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2).